Tel: +98-3137934940, Fax: +98-3136689732

Ε-mail:  m.mehrgardi@chem.ui.ac.ir

Webpage:   http://chem.ui.ac.ir/~m.mehrgardi

Professional / Research Experience

11/2012-present            Associate Professor of Chemistry, University of Isfahan, Iran

01/2008-11/2012            Assistant Professor of Chemistry, University of Isfahan, Iran

03/2006-01/2008          Assistant Professor of Chemistry, Institute for Advanced Studies in Basic Sciences (IASBS), Iran

06/2006-09/2006          Visiting Assistant Professor of Chemistry, University of Texas at Austin, TX, USA

07/2007-09/2007          Visiting Assistant Professor of Chemistry, University of Texas at Austin, TX, USA

07/2011-08/2011          Visiting Assistant Professor of Chemistry, Linkoping University, Linkoping, Sweden

07/2012-08/2012          Visiting Assistant Professor of Chemistry, Linkoping University, Linkoping, Sweden

06/2016-09/2016          Visiting Associate Professor of Chemistry, Auburn University, AL, USA

01/2017-02/2017          Visiting Associate Professor of Chemistry, Auburn University, AL, USA

06/2017-08/2017          Visiting Associate Professor of Chemistry, Auburn University, AL, USA

01/2018-02/2018          Visiting Associate Professor of Chemistry, Auburn University, AL, USA

06/2018-09/2018          Visiting Associate Professor of Chemistry, Auburn University, AL, USA

01/2019-02/2019          Visiting Associate Professor of Chemistry, Auburn University, AL, USA

 

Academic Background

09/2000-02/2006            Ph.D. in Analytical Chemistry, Department of Chemistry, Shiraz University, Shiraz, Iran.

                                    Supervisor: Prof. Abbaspour

09/2004-09/2005            Exchange  student  Fellowship,  University  of  Texas  at Austin, USA.

                                    Supervisor: Prof. Bard

09/1998-09/2000            M.Sc.    in   Analytical Chemistry,    Department of Chemistry, Shiraz University, Shiraz, Iran.

                                    Supervisor: Prof. Absalan

09/1993-02/1998            B.Sc. in Chemistry, University of Isfahan, Isfahan, Iran

                                                                                 

Main awards and achievements:

     Sep.  2013, Young Scientist award,  Advanced  Material  World  Congress,  Cesme, Izmir, Turkey.

     Dec. 2011, Guest Editor of Advanced Material Letters.

     Dec. 2011, Young Scientist award, International Conference on Nanotechnoly and Nanomaterials, New      Delhi, India.

     Dec 2011,    AML     award,   International      Conference        on         Nanotechnoly     and Nanomaterials, New Delhi, India.

 

Authorship Activity

▪     Peer-reviewed publications (published/in review):   50 total – 22 since 2014

▪     Google Scholar Statistics (as of January 2019): h-index: 17 (14 since 2014)

          Citations: 1001 (594 since 2014)

                                                                                 i10-index: 24 (17 since 2014)

     International Invited Presentations: 7

     National Presentations: 43 (Keynote: 8)

Teaching Experience:

-          Graduate Courses

•          Advanced electrochemistry

•          Bioelectrochemistry

•          Surface Analysis

•          Advanced Analytical chemistry

•          Advanced Spectroscopy

-          Undergraduate Courses

•          General Chemistry

•          Analytical Chemistry

•          Instrumental Analysis

•          Environmental Chemistry

•          Applied Electrochemistry

•          Laboratory of General Chemistry

•          Laboratory of Analytical Chemistry

•          Laboratory of Electrochemistry

•          Laboratory of Instrumental Analysis

 

Research Group Mentorship

-          2 Post-Doctoral Fellows

-          18 PhD Students

-          20 MSc Students

Experimental Techniques and Skills

   Proficient in

  Mammalian cell culture and basic cell and molecular biology skills.

  Different electrochemical techniques

  Fabricating nanostructured surfaces and synthesis of nanometrials

  Scanning electrochemical microscope

  Scanning electron microscope

  Atomic force microscope

  Surface modification with biomaterials.

 

Publications:

1.       A. Kefayat, F. Ghahremani, H. Motaghi, S. Rostami, M. A, Mehrgardi, “Alive attenuated Salmonella as a cargo shuttle for smart carrying of gold nanoparticles to tumour hypoxic regions” Journal of drug targeting, In-Press.

2.       H. Motaghi, M. A. Mehrgardi, “Spectrofluorometric Genotyping of single nucleotide polymorphisms using carbon dots as fluorophores” Spectrochimica Acta A 206 (2019) 154-159.

3.       M. Keshtkar, D. Shahbazi-Gahrouei, M. A. Mehrgardi, M. Aghaei, “Synthesis and Cytotoxicity Assessment of Gold-coated Magnetic Iron Oxide Nanoparticles” Journal of Biomedical Physics and Engineering, 8 (2018) 357-364.

4.       H. Motaghi, S. Ziyaee, M. A. Mehrgardi, A. A. Kajani, A. K. Bordbar, “Electrochemiluminescence detection of human breast cancer cells using aptamer modified bipolar electrode mounted into 3D printed microchannel” Biosensors and Bioelectronics 118 (2018) 217-223.

5.       F. Ghahremani, A, Kefayat, D. Shahbazi-Gahrouei, H. Motaghi, M. A. Mehrgardi, S. Haghjooy-Javanmard, “AS1411 aptamer-targeted gold nanoclusters effect on the enhancement of radiation therapy efficacy in breast tumor-bearing mice” Nanomedicine 9 (2018) 2563-3578.

6.       A. Abbasi Kajani, A. K. Bordbar, M. A. Mehrgardi, S. H. Zarkesh-Esfahani, H. Motaghi, M. Kardi, A. R. Khosropour, J. Ozdemir, M. Benamara, M. H. Beyzavi, “Green and Facile Synthesis of Highly Photoluminescent Multicolor Carbon Nanocrystals for Cancer Therapy and Imaging”, ACS Applied Biomaterials, 1 (2018) 1458-1467.

7.       M. Khodadadi, A. Malekpour, M. A. Mehrgardi, “Aptamer functionalized magnetic nanoparticles for effective extraction of ultratrace amounts of aflatoxin M1 prior its determination by HPLC” Journal of Chromatography A, 1564 (2018) 85-93.

8.       S. Yu, M. A. Mehrgardi, C. Shannon, “A bipolar electrochemical sensor with square wave excitation and ECL readout” Electrochemistry Communications 88 (2018) 24-28.                    

9.       S.M. Khoshfetrat, H. Bagheri, M. A. Mehrgardi, “Visual electrochemiluminescence biosensing of aflatoxin M1 based on luminol-functionalized, silver nanoparticle-decorated graphene oxide” Biosensors and Bioelectronics 100 (2018) 382-388.

10.   F. Ghahremani, D. Shahbazi-Gahrouei, A. Kefayat, H. Motaghi, M. A. Mehrgardi, “AS1411 aptamer conjugated gold nanoclusters as a targeted radiosensitizer for megavoltage radiation therapy of 4T1 breast cancer cells” RSC Advances 8 (2018), 4249-4258.

11.   L. E. Ahangar, M. A. Mehrgardi “Amplified detection of hepatitis B virus using an electrochemical DNA biosensor on a nanoporous gold platform” Bioelectrochemistry, 117 (2017) 83-88.

12.   H. Motaghi, M. A. Mehrgardi, P. Bouvet, “Carbon Dots-AS1411 Aptamer Nanoconjugate for Ultrasensitive Spectrofluorometric Detection of Cancer Cells” Scientific Reports 7 (2017), 10513.

13.   S.M. Khoshfetrat, M. A. Mehrgardi “Amplified detection of leukemia cancer cells using an aptamer-conjugated gold-coated magnetic nanoparticles on a nitrogen-doped graphene modified electrode” Bioelectrochemistry 114 (2017) 24-32.

14.   M.H. Mashhadizadeh, N. Naseri, M. A. Mehrgardi, “A simple non-enzymatic strategy for adenosine triphosphate electrochemical aptasensor using silver nanoparticle-decorated graphene oxide” Journal of the Iranian Chemical Society 14 (2017) 2007–2016.

15.   R. Poorghasem, R. S. Saberi, M.  Shayan, M. A. Mehrgardi, A. Kiani, “Closed Bipolar Electrochemistry for the Detection of Human Immunodeficiency Virus Short Oligonucleotide” Electrochimica Acta 222 (2017) 1483-1490.

16.   S. M. Khoshfetrat, M. A. Mehrgardi, “Amplified detection of leukemia cancer cells using an aptamer-conjugated gold-coated magnetic nanoparticles on a nitrogen-doped graphene modified electrode” Bioelectrochemistry 114 (2017) 24-32.

17.   M. F. Mousavi, S. Mirsian, A. Noori, H. Ilkhani, M. Sarparast, N. Moradi, S. Z. Bathaei, M. A. Mehrgardi, “BSA‐templated Pb Nanocluster as a Biocompatible Signaling Probe for Electrochemical EGFR Immunosensing” Electroanalysis 29 (2017) 861-872.

18.   M. Keshtkar, D. Shahbazi-Gahrouei, S. M. Khoshfetrat, M. A. Mehrgardi, M. Aghaei “Aptamer- conjugated magnetic nanoparticles as targeted magnetic resonance imaging contrast agent for breast cancer” Journal of Medical Signals and Sensors 6 (4), 243-247.

19.   F. Beigloo, A. Noori, M. A. Mehrgardi, M. F. Mousavi, “Label-free and sensitive impedimetric nanosensor for the detection of cocaine based on a supramolecular complexation with β- cyclodextrin, immobilized on a nanostructured polymer film” Journal of the Iranian Chemical Society 13 (4), 659-669.

20.   M. H. Mashhadizadeh, N. Naseri, M. A. Mehrgardi, “A digoxin electrochemical aptasensor using Ag nanoparticle decorated graphene oxide” Analytical Methods 8 (39), 7247-7253.

21.   N. Moradi, A. Noori, M. A. Mehrgardi, M. F. Mousavi, “Scanning electrochemical microscopy for electrochemical detection of single-base mismatches by tagging ferrocenecarboxylic acid as a redox probe to DNA” Electroanalysis, 28 (2016)823-832.

22.   F. Beigloo, A. Noori, M. A. Mehrgardi, M. F. Mousavi, “Label-free and sensitive impedimetric nanosensor for the detection of cocaine based on a supramolecular complexation with β- cyclodextrin, immobilized on a nanostructured polymer film” Journal of the Iranian Chemical Society 13 (2016) 659-559.

23.   S. M. Khoshfetrat , M. Ranjbari , M. Shayan , M. A. Mehrgardi, A. Kiani, “Wireless Electrochemiluminescence Bipolar Electrode Array for Visualized Genotyping of Single Nucleotide Polymorphism” Analytical Chemistry 87 (2015) 8123-8131.

24.   S.M. Khoshfetrat, M. A. Mehrgardi, “Amplified electrochemical genotyping of single-nucleotide polymorphisms using a graphene–gold nanoparticles modified glassy carbon platform” RSC Advances 5 (2015) 29285-29293.

25.   S.M. Khoshfetrat, M. A. Mehrgardi, "Dual amplification of single nucleotide polymorphism detection using graphene oxide and nanoporous gold electrode platform" Analyst, 139 (2014) 5192-5199.

26.   L. Kashefi-Kheyrabadi, M. A. Mehrgardi, E. Wiechec, A. P.F. Turner, A. Tiwari, “Ultrasensitive detection of human liver hepatocellular carcinoma (HepG2) cells using a label-free aptasensors”, Anal. Chem., 86 (2014) 4956-4960.

27.   S. Ghaderi, M. A. Mehrgardi, "Prussian blue-modified nanoporous gold film electrode foramperometric determination of hydrogen peroxide" Bioelectrochemistry, 98 (2014) 64-69.

28.   S.M. Khoshfetrat, M. A. Mehrgardi, "Electrochemical Genotyping of Single-Nucleotide Polymorphisms by using Monobase-Conjugated Modified Nanoparticles" ChemElectroChem, 1 (2014) 779-786.

29.   N. Moradi, M. F. Mousavi, M. A. Mehrgardi, A. Noori, "Preparation of a new electrochemical biosensor for single base mismatch detection in DNA" Analytical Methods, 5 (2013) 6531-6538.

30.   L. Kashefi-Kheyrabadi, M. A. Mehrgardi, “Aptamer-based electrochemical biosensor for detection of adenosine triphosphate using a nanoporous gold platform” Bioelectrochemistry, 94 (2013) 47-52.

31.   V. Alizadeh, M. A. Mehrgardi, M. F. Mousavi, “Electrochemical Investigation of Cytochrome c Immobilized onto Self-Assembled Monolayer of Captopril” Electroanalysis, 25 (2013) 1689-1696.

32.   L.E. Ahangar, M. A. Mehrgardi, “Nanoporous gold electrode as a platform for the construction of an electrochemical DNA hybridization biosensor” Biosensors and Bioelectronics, 38 (2012) 252-257.

33.   L. Kashefi-Kheyrabadi, M. A. Mehrgardi, “Aptamer-conjugated silver nanoparticles for electrochemical detection of adenosine triphosphate” Biosensors and Bioelectronics, 33 (2012) 94-98.

34.   L. Kashefi-Kheyrabadi, M. A. Mehrgardi, “Design and construction of a label free aptasensor for electrochemical detection of sodium diclofenac” Biosensors and Bioelectronics, 37 (2012) 184- 189.

35.   L.E. Ahangar, M. A. Mehrgardi, “3,4-Diaminobenzoic acid (DABA) as a redox label for electrochemical detection of single base mismatches” Electrochimica Acta, 56 (2011) 10264- 10269.

36.   M. A. Mehrgardi, L.E. Ahangar, “Silver nanoparticles as redox reporters for the amplified electrochemical detection of the single base mismatches” Biosensors and Bioelectronics, 26 (2011) 4308-4313.

37.   V. Alizadeh, M. F. Mousavi, M. A. Mehrgardi, S. H. Kazemi, H. Sharghi,” Electron Transfer  Kinetics of Cytochrome c Immobilized on a Phenolic Terminated Thiol Self Assembled Monolayer Determined by Scanning Electrochemical Microscopy” Electrochimica Acta, 56 (2011) 6224- 6229.

38.   M. N. Dehkordi, A.K. Bordbar, M. A. Mehrgardi, V. Mirkhani, “Spectrophotometric Study on the Binding of Two Water Soluble Schiff Base Complexes of Mn (III) with ct-DNA” Journal of Fluorescence, 21 (2011) 1649-1658.

39.   L.E. Ahangar, M. A. Mehrgardi, “Nanoparticle-functionalized nucleic acids: A strategy for amplified electrochemical detection of some single-base mismatches” Electrochimica Acta, 56 (2011) 2725-2729.

40.   M. A. Mehrgardi, R. Daneshtalab, “Electrochemical detection of different types of single-base mismatches in DNA using copper-phthalocyanine tetrasulfonic acid” Journal of Electroanalytical Chemistry, 650 (2011) 214-218.

41.   M. R. Azani, A. Hassanpour, A. K. Bordbar, M. A. Mehrgardi, “Interaction of calf thymus DNA with N, N′-Bis (3, 4-dihydroxybenzylidene)-1, 2-diaminobenzene ligands” Russian Journal of Physical Chemistry A, 84 (2010) 2284-2289.

42.   M. A. Mehrgardi, A. Barfidokht, “Electrocatalytic activity of thianthrene toward one-electron oxidation of guanosine and DNA in a non-aqueous medium” Journal of Electroanalytical Chemistry 644 (2010) 44–49.

43.   S. E. Salamifar, M. A. Mehrgardi, S. H. Kazemi, M. F. Mousavi, “Cyclic voltammetry and scanning electrochemical microscopy studies of methylene blue immobilized on the self- assembled monolayer of n-dodecanethiol”, Electrochimica Acta, 56 (2010) 896-904.

44.   S. E. Salamifar, M. A. Mehrgardi, M. F. Mousavi, “Ion transport and degradation studies of a polyaniline-modified electrode using SECM”  Electrochimica Acta 54 (2009) 4638–4646.

45.   Ran Tel-Vered, Darren A. Walsh, M. A. Mehrgardi, Allen J. Bard, "Carbon Nanofiber Electrodes and Controlled Nanogaps for Scanning Electrochemical Microscopy Experiments" Analytical Chemistry 8 (2006) 6959-6966.

46.   Abdolkarim Abbaspour, M. A. Mehrgardi, Abolhasan Noori, Mohammad Ali Kamyabi, Ali Khalafi-Nezhad, Mohammad Navid Soltani Rad, " Speciation of iron(II), iron(III) and full-range pH monitoring using paptode: A simple colorimetric method as an appropriate alternative for optodes" Sensors and Actuators B 113 (2006) 857–865.

47.   A. Abbaspour, M. A. Mehrgardi, “Electrocatalytic activity of Ce(III)-EDTA complex toward the oxidation of nitrite ion” Talanta 67 (2005) 579.

48.   A. Abbaspour, M. A. Mehrgardi, "Electrocatalytic Oxidation of Guanine and DNA on a Carbon Paste Electrode Modified by Cobalt Hexacyanoferrate Films" Analytical Chemistry 76 (2004) 5690.

49.   A. Abbaspour, M. A. Mehrgardi, R. Kia, “Electrocatalytic oxidation of guanine and ss-DNA at a cobalt (II) phthalocyanine modified carbon paste electrode”, Journal of Electroanalytical Chemistry, 568 (2004) 261-266.

50.   Absalan and M. A. Mehrgardi, "Separation and Preconcentration of Silver ion with 2- Mercaptobenzothiazole Immobilized on Surfactant-Coated Alumina", Separation and Purification Technology, 33 (2003) 95-101.

 

International seminars and Conferences:

1.       M. A. Mehrgardi, "Label-Free Aptamer Based Electrochemical Biosensors: A simple way to sensitive diagnosis of Cancer Cells" Advance Material World Congress, 16-19 Sep. 2013, Izmir, Turkey.

2.       M. A. Mehrgardi,"", International Conference on Nnomterials and Nanotechnology, 18-21 Dec. 2011, University of Delhi, New Delhi, India.

3.       M. A. Mehrgardi, A. Tavakkoli,"Nanoparticle functionalized Nucleic Acids: A new Strategy for Construction of DNA Hybridization Biosensors", Frontiers of Chemical Sciences VI: Research and Education in the Middle East, Nov. 14-19, Amman, Jordan.

4.       Abbaspour, M. A. Mehrgardi, “Electrocatalytic Oxidation of Guanine and DNA on Carbon Paste Electrode Modified by Cobalt Hexacyanoferrate Films” International conference on Molecule to Materials, Sant Longowal Institute of eng. & Tech., Longowal, Punjab, India, p. 88

5.       M. A. Mehrgardi, A. J. Bard, " Application of Scanning Electrochemical Microscopy to Charge Transfer Measurements on Self-Assembled Monolayers of Matched and Mismatched DNA", Pittcon 2006.

 

National Seminars and Conferences:

1.       M. A. Mehrgardi, "Genotyping of Single Nucleotide Polymorphism", 20th Iranian Analytical Chemistry Conference, 25-27 Feb. 2014, Isfahan University of Technology, Iran (Invited Speaker).

2.       H. Dadkhah, M. A. Mehrgardi, "Aptazyme Based electrochemical biosensor for the amplified adenosine triphosphate and lead ion detection", 20th Iranian Analytical Chemistry Conference, 25-27 Feb. 2014, Isfahan University of Technology, Iran.

3.       M. A. Mehrgardi, "Aptamers: A Bright New Horizon in Interdisciplinary Science", 24-26 Feb. 2013, Ferdosi University, Mashhad, Iran (Invited Speaker).

4.       M. Tavahodi, M. A. Mehrgardi, “UV–visible spectrophotometric, voltammetric studies and circular dichroism of the interaction of Alizarin Red S with calf thymus DNA”, 16th Iranian Seminar of Analytical Chemistry, July 28-30, 2009, Bu Ali Sina University, Hamadan, Iran.

5.       A. Tavakkoli, M. A. Mehrgardi, “Electrochemical Detection of Different Types of Single Base Mismatches in DNA using Alizarine Red S as a Negatively Charged Intercalator” 16th Iranian Seminar of Analytical Chemistry, July 28-30, 2009, Bu Ali Sina University, Hamadan, Iran.

6.       Reza Daneshtalab, M. A. Mehrgardi, “Electrochemical and Spectroscopic Studies on the Interactions of Copper-Phthalocyanine Dye with Herring Sperm, and Calf Thymus DNA” 16th Iranian Seminar of Analytical Chemistry, July 28-30, 2009, Bu Ali Sina University, Hamadan, Iran.

7.       M. A. Mehrgardi, R. Daneshtalab, , “Electrochemical Detection of Single Base Mismatches in DNA using Copper-Phthalocyanine Tetrasulfonic Acid”, 16th Iranian Seminar of Analytical Chemistry, July 28-30, 2009,  Bu Ali Sina University, Hamadan, Iran.

8.       M. A. Mehrgardi, “Electrochemical Investigations of Charge Transfer through DNA: Fundamentals, Challenges and Applications” Keynote speaker, 8th Iranian Biennial Seminar of Electrochemistry, July 14-16, 2009, University of Kurdistan, Iran.

9.       M. A. Mehrgardi, A. Tavakkoli, “Using of Pt-Nanoparticle for detection of single base mismatches in DNA”, 8th Iranian Biennial Seminar of Electrochemistry, July, 14-16, 2009, University of Kurdistan, Iran.

10.   S. Habibigohar, M. A. Mehrgardi, “Electrocatalytic oxidation of guanine at the surface of a CNT- modified CoHCF modified glassy carbon electrode” 8th Iranian Biennial Seminar of Electrochemistry, July, 14-16, 2009, University of Kurdistan, Iran.

11.   E. Salamifar, M. F. Mousavi, V. Alizadeh, M. A. Mehrgardi, H. Kazemi, “ Electrochemical studies of methylene blue at thiol SAMs-modified gold electrodes” 8th Iranian Biennial Seminar of Electrochemistry, July, 14-16, 2009, University of Kurdistan, Iran.

12.   M. A. Mehrgardi, “Electrochemistry of DNA” Keynote Speaker, 1st regional symposium on Bioelectrochemistry, 13-15 October 2008, University of Tehran, Tehran, Iran.

13.   G. Absalan, M. A. Mehrgardi, “Application of 2-Mercaptobenzothiazole Immobilized on Surfactant Coated Alumina for Separation and Preconcentration of Copper (II) Ion” poster No. P4-34 presented at 11th Iranian Seminar of Analytical Chemistry, 29-31 January 2002, Yazd University, Yazd, Iran.

14.   G. Absalan,  M. A. Mehrgardi, "Separation and Preconcentration of Silver ion with 2- Mercaptobenzothiazole Immobilized on Surfactant-Coated Alumina", poster No. P2-25, presented at 10th Iranian Seminar of Analytical Chemistry, Sharif University of  Technology, Tehran, Iran, 6-8 February 2001; proceeding, p.190-191.

15.   G. Absalan, M. A. Mehrgardi, R. Kamali, “Solid Phase Extraction of Trace Amounts of Silver Ion using 1-(2-Pyridylazo) 2-Naphthol Immobilized on Surfactant-Coated Alumina” poster No. P4-36 presented at 11th Iranian Seminar of Analytical Chemistry, Yazd University, Yazd, Iran, 29-31 January 2002; proceeding, p.270.

Workshops:

1.       2nd Iranian-Indian Conference in Nanotechnology, 5-7 May 2009, "Scanning Electrochemical Microscopic imaging and its application in biological systems" in "Instrumental Analysis and Imaging Nano-sized Material" workshop

2.       "Application of Advanced Molecular Methods for Diagnosis of Human Genetic Disease" National Institute of Genetic Engeneering and Biotechnology, 13-16 May 2008, Tehran, Iran.